Anti-FLI1 Anticorpo [FLI1/1312] (A248550)

Anti-FLI1 Antibody [FLI1/1312]

Mouse monoclonal [FLI1/1312] antibody to FLI1.

This antibody recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus.Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewings Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

Flow Cytometry, IF, WB

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 107-261, of human FLI1 protein with hexa-histidine tag.

Mouse

Monoclonal

FLI1/1312

IgG1

kappa

Protein A chromatography.

200 µg/ml

51 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FLI1 Antibody [FLI1/1312] - BSA and Azide free (A251732).

ERGB transcription factor, Ewing Sarcoma breakpoint region 2, EWSR 2, EWSR2, FLI 1, FLI 1 proto oncogene, Fli-1 proto-oncogene, ETS transcription factor, FLI1 EWS fusion gene, FLI1 proto oncogene, FLI1_HUMAN, Friend leukemia integration 1 (FLI1) transcription factor, Friend leukemia integration 1 transcription factor, Friend leukemia virus integration 1, Proto-oncogene Fli-1, Sarcoma breakpoint region 2 (EWSR2), SIC 1, SIC1, Transcription factor ERGB, Viral integration region FLI1, Viral integration region FLI1, mouse, homolog of