Anti-Fibroblast Activation Proteina, alpha Anticorpo (A283098)

$645

Anticorpo policlonale di coniglio contro Fibroblast Activation Protein, alpha per IHC-P.

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com

Prodotti consigliati per Anti-Fibroblast Activation Protein, alpha Anticorpo

Nome
Anti-Fibroblast Activation Protein, alpha Antibody
Descrizione
Rabbit polyclonal antibody to Fibroblast Activation Protein, alpha.
Specificità
This antibody recognises fibroblast activation protein alpha (FAP alpha), a type II membrane protein belonging to the serine protease family. FAP alpha is upregulated on activated fibroblasts in response to wounding, and may also be involved in epithelial-mesenchymal interactions during development and tissue repair. Active FAP alpha is a ~170 kDa homodimeric protein which can also exist as a soluble form. FAP alpha can also form heterodimeric complexes with CD26 (DPP4), and these proteins may function co-ordinately to modulate the growth, differentiation, adhesion and metastasis of tumour cells.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P 1: 10 µg/ml
Reattività
Human
Immunogeno
Synthetic peptide corresponding to a region within the extracellular domain of human FAP alpha, conjugated to Keyhole Limpet Haemocyanin.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare

Unconjugated

Concentrazione
500 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Rabbit anti Human FAP alpha antibody detects fibroblast activation protein alpha (FAP alpha), a type II membrane protein belonging to the serine protease family. FAP alpha is upregulated on activated fibroblasts in response to wounding, and may also be involved in epithelial-mesenchymal interactions during development and tissue repair. Active FAP alpha is a ~170 kDa homodimeric protein which can also exist as a soluble form. FAP alpha can also form heterodimeric complexes with CD26 (DPP4), and these proteins may function co-ordinately to modulate the growth, differentiation, adhesion and metastasis of tumour cells.
Sinonimi
170 kDa melanoma membrane bound gelatinase, 170 kDa melanoma membrane-bound gelatinase, DPPIV, FAP, FAPA, Fibroblast activation protein alpha, Integral membrane serine protease, Seprase, SEPR_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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