Rabbit polyclonal antibody to Ezrin (phospho Thr567).
Specificità
This antibody recognises ezrin, also known as villin-2, when phosphorylated at threonine 567. Ezrin is a member of the Ezrin Radixin Moesin (ERM) family. Ezrin functions as a linker molecule between the plasma membrane and the cytoskeleton. Phosphorylation of ezrin at threonine 567 regulates binding to F-actin and the cell membrane.
Applicazioni
WB
Diluizioni consigliate
WB: 1:500 - 1:2,000
Reattività
Human, Mouse, Rat
Immunogeno
Phospho-specific peptide corresponding to residues surrounding Thr567 of human ezrin.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Concentrazione
Lot Specific
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Conservazione
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Note generali
Rabbit anti ezrin (pThr567) antibody recognizes ezrin, also known as villin-2, when phosphorylated at threonine 567. Ezrin is a member of the Ezrin Radixin Moesin (ERM) family. Ezrin functions as a linker molecule between the plasma membrane and the cytoskeleton. Phosphorylation of ezrin at threonine 567 regulates binding to F-actin and the cell membrane (Zhu et al. 2007).
Sinonimi
CVIL, CVL, Cytovillin, Cytovillin 2, DKFZp762H157, Epididymis secretory protein Li 105, EZR, EZRI_HUMAN, FLJ26216, HEL S 105, MGC1584, p81, VIL 2, VIL2, Villin 2, Villin 2 (ezrin), Villin 2 ezrin, Villin-2, Villin2