Mouse monoclonal [SULT1E1/7124] antibody to Estrogen Sulfotransferase.
Specificità
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Applicazioni
WB, IHC-P
Controllo positivo
HEPG2 cells. Human liver, intestine or kidney.
Diluizioni consigliate
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 100-294) of human SULT1E1 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
SULT1E1/7124
Isotipo
IgG2
Catene leggere
kappa
Coniugare
Unconjugated
Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
35 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
EST, EST-1, EST1, estrogen-preferring, estrone sulfotransferase, ST1E1, ST1E1_HUMAN, STE, Sulfotransferase, Sulfotransferase 1E1, Sulfotransferase estrogen preferring, Sulfotransferase family 1E member 1, SULT1E1
![Immunohistochemistry - Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] (A250068) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250068_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] - BSA and Azide free (A253248) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253248_1.jpg?profile=product_alternative)
