Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] - BSA and Azide free
Descrizione
Mouse monoclonal [CPTC-SULT1E1-1] antibody to Estrogen Sulfotransferase.
Specificità
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Applicazioni
WB, IHC-P
Diluizioni consigliate
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human SULT1E1 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
CPTC-SULT1E1-1
Isotipo
IgG2b
Catene leggere
kappa
Coniugare
Unconjugated
Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
35 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human small intestine using Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1].
SDS-PAGE analysis of Anti-Estrogen Sulfotransferase Antibody [CPTC-SULT1E1-1] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.