Rabbit polyclonal antibody to eIF4EBP1 (phospho Ser65).
Applicazioni
WB
Diluizioni consigliate
WB: 1:500 - 1:2,000
Reattività
Human, Mouse, Rat
Immunogeno
Phospho-specific peptide corresponding to residues surrounding Ser65 of human 4EBP1.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Concentrazione
Lot Specific
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Conservazione
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Note generali
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is also known as phosphorylated heat-and acid-stable protein regulated by insulin 1 (PHAS-I), when phosphorylated at serine 65. 4EBP1 belongs to the eIF4E-binding protein family. 4EBP1, when bound to eIF4E, inhibits cap-dependent translation. Phosphorylation at serine 65 inhibits binding of 4EBP1 to eIF4F allowing cap-dependent translation.
Sinonimi
4E-BP1, 4EBP1, 4EBP1_HUMAN, BP 1, eIF4E binding protein 1, eIF4E-binding protein 1, Eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, PHASI, Phosphorylated heat- and acid-stable protein regulated by insulin 1
