Anti-E2F6 Anticorpo [PCRP-E2F6-1F8] (A251562)

Anticorpo monoclonale [PCRP-E2F6-1F8] di topo contro E2F6 per Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-E2F6 Antibody [PCRP-E2F6-1F8] - BSA and Azide free
Descrizione
Mouse monoclonal [PCRP-E2F6-1F8] antibody to E2F6.
Specificità
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
Applicazioni
Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human E2F6 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PCRP-E2F6-1F8
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
35 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-E2F6 Antibody [PCRP-E2F6-1F8] (A254378).
Sinonimi
E2F 6, E2F binding site modulating activity protein, E2F transcription factor 6, E2F transcription factor 6 isoform 1, E2F-6, E2F6_HUMAN, EMA, MGC111545, Transcription factor E2F6
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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