Anti-DR4 Anticorpo (A283854)

Anti-DR4 Antibody

Rabbit polyclonal antibody to DR4.

This antibody recognises the ~57 kDa apoptosis related protein designated Death receptor 4, also known as CD261 or DR4. CD261 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus CD261 has also been called TRAIL-RI. CD261 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.

WB, IHC-Fr

WB: 1:500 - 1:1,000

Human

A peptide corresponding to the C-terminus of human CD261 (DR4).

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human CD261 antibody recognizes the ~57 kDa apoptosis related protein designated Death receptor 4, also known as CD261 or DR4. CD261 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus CD261 has also been called TRAIL-RI. CD261 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.

Apo2, CD261, Cytotoxic TRAIL receptor, Death receptor 4, NF related apoptosis-inducing ligand receptor 1, TNF receptor superfamily member 10a, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TR10A_HUMAN, TRAIL receptor 1, TRAIL-R1, TRAILR 1, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Tumor necrosis factor receptor superfamily member 10a variant 2, Tumor necrosis factor receptor superfamily, member 10a