This antibody recognises CRM197 , a non-toxic mutant form of diphtheria toxin with an amino acid substitution at glycine-52 to glutamic acid.
Applicazioni
ELISA
Reattività
Bacterial
Immunogeno
Purified diphtheria toxoid.
Specie ospite
Goat
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Concentrazione
5 mg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Diphtheria toxin is an exotoxin secreted by various strains of Corynebacterium diphtheriae that is the cause of diphtheria. The active toxin is a single chain of 535 amino acids composed of 3 distinct structural/functional domains; and N-Terminal ADP-ribosyltransferase (catalytic domain); a region which facilitates the delivery of the catalytic domain across the cell membrane (transmembrane domain) and the eukaryotic cell receptor binding domain.