Ricombinante Anti-Decorin Anticorpo [rDCN/9075] (A314880)

Anti-Decorin Antibody [rDCN/9075]

Recombinant mouse monoclonal [rDCN/9075] antibody to Decorin.

Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

IHC-P

Human prostate or skin tissue (IHC).

IHC: 1-2 µg/ml

Human

Recombinant human Decorin protein fragment (around Amino Acids 200-359). The exact sequence is proprietary.

Mouse

Monoclonal

rDCN/9075

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

43 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Bone proteoglycan II, CSCD, DCN, DCN protein, Decorin proteoglycan, Dermatan sulphate proteoglycans II, DKFZp686J19238, DSPG 2, DSPG2, PG 40, PG II, PG S2, PG-S2, PG40, PGII, PGS 2, PGS2, PGS2_HUMAN, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B