Anti-Cyclin D1 Antibody (A282770)

Anti-Cyclin D1 Antibody

Rabbit polyclonal antibody to Cyclin D1.

This antibody recognises Cyclin D1, a member of the cyclin family that function as CKD reculators. Cyclin D1 is involved in cell cycle transition and has been shown to interact with the retinoblastoma protein. The unprocessed precursor is 295 amino acids long. It is expressed in abnormally high levels in a number of cancers and is specifically implicated in breast cancer development.

WB, ELISA

ELISA: 1:2,000 - 1:10,000, WB: 1:500 - 1:1,000, When used on asynchronous HN30 cell lysates, a band was observed at approximately 34 kDa corresponding to Cyclin D1.

Human, Mouse, Dog, Chimpanzee, Amphibia, Zebrafish, Rat

Full length synthetic polypeptide corresponding to the human gene sequence.

Rabbit

Polyclonal

IgG

Delipidation, defibrinated and sterile filtered.

Approximately 34 kDa corresponding to Cyclin D1 in asynchronous HN30 cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.01% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti cyclin D1 antibody recognizes Cyclin D1, a member of the cyclin family that function as CKD reculators. Cyclin D1 is involved in cell cycle transition and has been shown to interact with the retinoblastoma protein. The unprocessed precursor is 295 amino acids long. It is expressed in abnormally high levels in a number of cancers and is specifically implicated in breast cancer development.

B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1, CCND1, G1/S-specific cyclin-D1, PRAD1, PRAD1 oncogene