This antibody recognises cyclin-A also known as cyclin-A2. Cyclin-A is a member of the cyclin protein family and plays a critical role in the regulation of the cell cycle through its interaction with cyclin dependent kinases (CDKs). Binding of cyclins to CDKs is essential for activation of their kinase activity.
Applicazioni
WB
Diluizioni consigliate
WB: 1:200
Reattività
Mouse, Human, Rat
Immunogeno
A peptide corresponding to the C-terminus of mouse cyclin-A.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Purificazione
Affinity chromatography.
Concentrazione
200 µg/ml
Peso molecolare
Approximately 60 kDa when run under reducing conditions.
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.2% Gelatin and 0.1% Sodium Azide.
Conservazione
Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
Note generali
Rabbit anti cyclin-A antibody recognizes cyclin-A also known as cyclin-A2. Cyclin-A is a member of the cyclin protein family and plays a critical role in the regulation of the cell cycle through its interaction with cyclin dependent kinases (CDKs). Binding of cyclins to CDKs is essential for activation of their kinase activity (Enserink and Kolodner 2010).