This antibody recognises cyclin-A also known as cyclin-A2. Cyclin-A is a member of the cyclin protein family and plays a critical role in the regulation of the cell cycle through its interaction with cyclin dependent kinases (CDKs). Binding of cyclins to CDKs is essential for activation of their kinase activity.
Applications
WB
Dilutions
WB: 1:200
Reactivity
Mouse, Human, Rat
Immunogen
A peptide corresponding to the C-terminus of mouse cyclin-A.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Purification
Affinity chromatography.
Concentration
200 µg/ml
Molecular Weight
Approximately 60 kDa when run under reducing conditions.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.2% Gelatin and 0.1% Sodium Azide.
Storage
Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti cyclin-A antibody recognizes cyclin-A also known as cyclin-A2. Cyclin-A is a member of the cyclin protein family and plays a critical role in the regulation of the cell cycle through its interaction with cyclin dependent kinases (CDKs). Binding of cyclins to CDKs is essential for activation of their kinase activity (Enserink and Kolodner 2010).