This antibody recognises human CXCL9, otherwise known as MIG (monokine induced by Interferon-gamma), a member of the CXC family of chemokine receptors, secreted by interferon stimulated monocytes, macrophages and endothelial cells. CXCL9 signals through binding to CD183 (CXCR3).CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant, and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumou growth inhibition and angiogenesis. CXCL9 is active against E.coli, S.aureus, L.monocytogenes and S.pyogenes.

Applicazioni

WB, ELISA, IHC-P, Functional Assays

Diluizioni consigliate

ELISA: 0.5 - 2 µg/ml, Functional Assays: 5.0 - 7.0 µg/ml, WB: 0.1 - 0.2 µg/ml

Reattività

Human

Immunogeno

Recombinant human CXCL9.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

1 mg/ml after reconstitution.

Forma del prodotto

Lyophilized

Ricostituzione

Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Formulazione

Supplied in Phosphate Buffered Saline.

Conservazione

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Note generali

Rabbit anti Human CXCL9 polyclonal antinbody recognizes human CXCL9, otherwise known as MIG (monokine induced by Interferon-gamma), a member of the CXC family of chemokine receptors, secreted by interferon stimulated monocytes, macrophages (Muller et al. 2010) and endothelial cells (Loos et al. 2006). CXCL9 signals through binding to CD183 (CXCR3).CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant, and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumou growth inhibition and angiogenesis (Whiting et al. 2004) . CXCL9 is active against E.coli, S.aureus, L.monocytogenes (Cole et al. 2001) and S.pyogenes (Egesten et al. 2007).

Sinonimi

C-X-C motif chemokine 9, Chemokine (C-X-C motif) ligand 9, Chemokine, CXC motif, ligand 9, CMK, Crg 10 , CXCL9_HUMAN, Gamma interferon induced monokine, Gamma-interferon-induced monokine, HuMIG, MIG, Monokine induced by gamma interferon, Monokine induced by interferon gamma, Monokine induced by interferon-gamma, SCYB9, Small inducible cytokine B9, Small inducible cytokine subfamily B member 9, Small-inducible cytokine B9

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.