This antibody recognises the carboxy-terminus of type VII collagen. Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components. Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain. Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin.

Applicazioni

IHC-Fr

Diluizioni consigliate

IHC-Fr: 1:25 - 1:100

Reattività

Human

Reattività incrociata

This antibody does not cross react with Rat, Mouse, or Pig

Immunogeno

Crude extract of skin.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

LH7.2

Isotipo

IgG1

Coniugare

Unconjugated

Purificazione

Protein A affinity chromatography of tissue culture supernatant.

Concentrazione

1 mg/ml

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Mouse anti Human collagen VII antibody, clone LH7.2 recognizes the carboxy-terminus of type VII collagen (Kirkham et al. 1989). Collagen VII is a basement membrane protein in stratified squamous epithelia which is involved in membrane organization through interaction with other ECM components (Gammon et al. 1992). Collagen VII is composed of three identical alpha chains, each having an amino-terminal non-collagenous domain and a carboxy-terminal collagenous domain.Mouse anti Human collagen VII, clone LH7.2 has proved effective for immunohistochemical identification of basement membrane in human skin (Watson et al. 2001).

Sinonimi

Alpha 1 type VII collagen, CO7A1_HUMAN, Col7a1, Collagen alpha 1(VII) chain, Collagen alpha-1(VII) chain, Collagen type VII alpha 1, Collagen VII alpha 1 polypeptide, CollagenVII, EBD 1, EBD1, EBDCT, EBR 1, EBR1, LC collagen, Long chain collagen, Long-chain collagen

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.