Anti-Glypican 3 Anticorpo (A323365)

HEPG2 cells were stained with Codrituzumab Biosimilar - Anti-Glypican 3 Antibody - Low endotoxin, Azide free (A323365) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.

Immobilized recombinant human GPC3 protein (His tag) at 2 µg/ml is bound by Codrituzumab Biosimilar - Anti-Glypican 3 Antibody - Low endotoxin, Azide free (A323365). EC₅₀ = 0.008741 µg/ml.

Codrituzumab Biosimilar - Anti-Glypican 3 Antibody - Low endotoxin, Azide free (A323365) induced ADCC activity was evaluated using human GPC3 CHOS Cell. The max Lysis rate was approximately 30%.

The endocytosis ratio of Codrituzumab Biosimilar - Anti-Glypican 3 Antibody - Low endotoxin, Azide free (A323365) by HuH-7 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40%at antibody concentration of 1 nM.

Huh-7 cells were stained with Codrituzumab Biosimilar - Anti-Glypican 3 Antibody - Low endotoxin, Azide free (A323365) and negative control protein respectively, washed and then followed by PE and analyzed with FACS.