Anti-Clostridium difficile Toxin B Anticorpo [5158] (A278815)

$340

Anticorpo monoclonale [5158] di topo contro Clostridium difficile Toxin B per ELISA.

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Clostridium difficile Toxin B Antibody [5158]
Descrizione
Mouse monoclonal [5158] antibody to Clostridium difficile Toxin B.
Specificità
This antibody recognises Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modify the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Applicazioni
ELISA
Diluizioni consigliate
ELISA: 1:20 - 1:200
Reattività
Bacterial
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
5158
Isotipo
IgG1
Coniugare

Unconjugated

Purificazione
Protein A affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Mouse anti Clostridium difficile Toxin B antibody, clone 5158 recognizes Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modify the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Sinonimi
C. difficile Toxin B, Cytotoxin B, tcdB, toxB, Toxin B
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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