Rabbit polyclonal antibody to Cdk6 (phospho Tyr24).
Specificità
This antibody recognises cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6.
Applicazioni
WB, IHC-P
Diluizioni consigliate
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000
Reattività
Human, Mouse
Immunogeno
Phospho-specific peptide corresponding to residues surrounding Tyr24 of human Cdk6.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare
Unconjugated
Concentrazione
Lot Specific
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Conservazione
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
Note generali
Rabbit anti Cdk6 (pTyr13) recognizes cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6 (Bertero et al. 2013).