Anti-Cdk6 (phospho Tyr24) Anticorpo (A283574)

Anti-Cdk6 (phospho Tyr24) Antibody

Rabbit polyclonal antibody to Cdk6 (phospho Tyr24).

This antibody recognises cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6.

WB, IHC-P

IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000

Human, Mouse

Phospho-specific peptide corresponding to residues surrounding Tyr24 of human Cdk6.

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Cdk6 (pTyr13) recognizes cyclin-dependent kinase 6 (Cdk6) also known as cell division protein kinase 6 or serine/threonine-protein kinase PLSTIRE, when phosphorylated at tyrosine 13. Cdk6 is a member of the serine/threonine protein kinase family and is involved in regulation of cell-cycle progression during G1 phase and transition from G1 to S phase. Phosphorylation of Cdk6 at tyrosine 24 inhibits the kinase activity of Cdk6 (Bertero et al. 2013).

CDK 6, CDK6_HUMAN, Cell division protein kinase 6, Crk 2, Crk2, Cyclin dependent kinase 6, Cyclin-dependent kinase 6, MCPH12, MGC59692, p40, PLSTIRE, Serine/threonine protein kinase PLSTIRE, Serine/threonine-protein kinase PLSTIRE, STQTL11