Note generali
Mouse anti Human CD8 beta antibody, clone 2ST8.5H7 recognizes the human CD8 cell surface antigen. The antibody binds to the beta chain, recognizing an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.CD8 molecules are composed of dimers of either alpha/alpha or alpha/beta polypeptide combinations. Both types of dimer may co-exist at the cell surface. Clone 2ST8.5H7 is also referred to as clone T8/2T8-5H7 and binding is dependent on the expression of the alpha/beta dimer.