Anti-CD7 Anticorpo [B-F12] (A250544)

Anticorpo monoclonale [B-F12] di topo contro CD7 per Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-CD7 Antibody [B-F12]
Descrizione
Mouse monoclonal [B-F12] antibody to CD7.
Specificità
This antibody recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Applicazioni
Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Immunogeno
Chronic Lymphoid Leukemia cells (CLL).
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
B-F12
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
40 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD7 Antibody [B-F12] - BSA and Azide free (A253724).
Sinonimi
CD7 antigen, CD7 antigen (p41), CD7 molecule, CD7_HUMAN, GP40, LEU 9, LEU9, p41 protein, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp 40, Tp40, TP41
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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