Anti-CD63 Anticorpo [MEM-259] (A281145)

$145

Anticorpo monoclonale [MEM-259] di topo contro CD63 per IP, Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-CD63 Antibody [MEM-259]
Descrizione
Mouse monoclonal [MEM-259] antibody to CD63.
Specificità
This antibody recognises the CD63 cell surface antigen, also known as granulophysin, lysozomal associated membrane protein 3 (LAMP-3), Melanoma-associated antigen ME491, Ocular melanoma-associated antigen or tetraspanin-30. CD63 is a 238 amino acid, tetraspanin glycoprotein of ~40-60 kDa.CD63 is expressed by monocytes, macrophages, endothelial cells where it is a component of Weibel-Palade bodies and by a variety of cell lines. It is located intracellularly in lysosomal granules of platelets, being translocated to the surface upon activation. It may therefore by useful as a marker of platelet activation. CD63 expression is also associated with melanoma development and expression is rapidly down-regulated by progesterone in endometrial tissues.
Applicazioni
IP, Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1:25 - 1:100, Use 10µl of the suggested working dilution to label 106 cells in 100µl or 100µl whole blood
Reattività
Human
Immunogeno
HPB-ALL cell line.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
MEM-259
Isotipo
IgG1
Coniugare

Unconjugated

Purificazione
Protein A affinity chromatography of tissue culture supernatant.
Concentrazione
1 mg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Mouse anti Human CD63 antibody, clone MEM-259 recognizes the CD63 cell surface antigen, also known as granulophysin, lysozomal associated membrane protein 3 (LAMP-3), Melanoma-associated antigen ME491, Ocular melanoma-associated antigen or tetraspanin-30. CD63 is a 238 amino acid, tetraspanin glycoprotein of ~40-60 kDa.CD63 is expressed by monocytes, macrophages, endothelial cells where it is a component of Weibel-Palade bodies (Vischer et al. 1993) and by a variety of cell lines. It is located intracellularly in lysosomal granules of platelets, being translocated to the surface upon activation. It may therefore by useful as a marker of platelet activation (Hamamoto et al. 1994). CD63 expression is also associated with melanoma development (Radford et al. 1997) and expression is rapidly down-regulated by progesterone in endometrial tissues (Okada et al. 1999).
Sinonimi
CD 63, CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 antigen melanoma 1 antigen, CD63 molecule, CD63_HUMAN, gp55, Granulophysin, LAMP 3, LAMP-3, LAMP3, LIMP, Lysosomal associated membrane protein 3, Lysosomal-associated membrane protein 3, Lysosome associated membrane glycoprotein 3, Mast cell antigen AD1, ME491, Melanoma 1 antigen, Melanoma associated antigen ME491, Melanoma associated antigen MLA1, Melanoma-associated antigen ME491, MGC72893, MLA 1, MLA1, NGA, Ocular melanoma associated antigen, Ocular melanoma-associated antigen, OMA81H, PTLGP40, Tetraspanin 30, Tetraspanin-30, Tspan 30, Tspan-30, TSPAN30
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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