Recombinant rabbit monoclonal [C6/7022R] antibody to CD6.
Specificity
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human CD6 protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
C6/7022R
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
90-130 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human spleen using Anti-CD6 Antibody [C6/7022R] at 2µg/ml in PBS for 30 minutes at room temperature. Inset: PBS instead of the primary antibody. Secondary antibody negative control.
SDS-PAGE analysis of Anti-CD6 Antibody [C6/7022R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
Publishing research using Recombinant Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682)? Please let us know so that we can list the citation on this page.
Alternative products to Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_1.jpg?profile=product_top)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_2.jpg?profile=product_top)
![SDS-PAGE - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_3.jpg?profile=product_top)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_1.jpg?profile=product_top_thumb)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_2.jpg?profile=product_top_thumb)
![SDS-PAGE - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_3.jpg?profile=product_top_thumb)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_1.jpg?profile=product_image)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_2.jpg?profile=product_image)
![SDS-PAGE - Anti-CD6 Antibody [C6/7022R] - BSA and Azide free (A278682) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278682_3.jpg?profile=product_image)
![Immunohistochemistry - Anti-CD8 Antibody [C6/2884R] - BSA and Azide free (A253723) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253723_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-CD6 Antibody [C6/2884R] (A250543) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250543_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-CD6 Antibody [3F7B5] (A250538) - Antibodies.com](https://cdn.antibodies.com/image/catalog/250/A250538_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-CD6 Antibody [3F7B5] - BSA and Azide free (A253718) - Antibodies.com](https://cdn.antibodies.com/image/catalog/253/A253718_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-CD6 Antibody [C6/7022R] (A278094) - Antibodies.com](https://cdn.antibodies.com/image/catalog/278/A278094_1.jpg?profile=product_alternative)
