Recombinant Anti-CD43 Antibody [SPN/6562R] - BSA and Azide free (A278654)

Anti-CD43 Antibody [SPN/6562R] - BSA and Azide free

Recombinant rabbit monoclonal [SPN/6562R] antibody to CD43.

It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human CD43 protein.

Rabbit

Monoclonal

SPN/6562R

IgG

kappa

Protein A chromatography.

1 mg/ml

95 kDa / 115 kDa / 135 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD43 Antibody [SPN/6562R] (A278066).

Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, Sialophorin, SPN