Anti-CD36 Anticorpo [185-1G2] (A253866)

Anticorpo monoclonale [185-1G2] di topo contro CD36 per Functional Studies, Flow Cytometry e IF.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-CD36 Antibody [185-1G2] - BSA and Azide free
Descrizione
Mouse monoclonal [185-1G2] antibody to CD36.
Specificità
This antibody recognizes a protein of 80kDa-90kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Applicazioni
Functional Studies, Flow Cytometry, IF
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reattività
Human
Immunogeno
Stimulated human leukocytes.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
185-1G2
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
80-90 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD36 Antibody [185-1G2] (A250686).
Sinonimi
Adipocyte membrane protein, BDPLT10, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule, CD36 molecule (thrombospondin receptor), CD36_HUMAN, CHDS7, Cluster determinant 36, Collagen receptor, platelet, FAT, Fatty acid translocase, Fatty acid transport protein, Glycoprotein IIIb, GP IIIb, GP3B, GP4, GPIIIB, GPIV, Leukocyte differentiation antigen CD36, MGC108510, MGC91634, PAS 4 protein, PAS IV, PAS-4, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, scarb3, Scavenger receptor class B member 3, Thrombospondin receptor
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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