Anti-CD28 Antibody [CB28] (CF® 488) (A251161)

Anti-CD28 Antibody [CB28] (CF® 488)

Mouse monoclonal [CB28] antibody to CD28 (CF® 488).

This antibody recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Flow Cytometry, IF

Flow Cytometry: 5 µl / million cells or 5 µl / 100 µl whole blood, IF: 1:50-1:100

Human

Recombinant human CD28 protein.

Mouse

Monoclonal

IgG1

kappa

Protein A/G chromatography.

100 µg/ml

44 kDa (monomer) / 88 kDa (dimer)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Store at 4-8°C. Antibody is stable for 24 months.

T-cell-specific surface glycoprotein CD28, TP44

This product is for research use only. It is not intended for diagnostic or therapeutic use.