Anti-CD163 Anticorpo [EDHu-1] (FITC) (A280342)

$420

Anticorpo monoclonale [EDHu-1] di topo contro CD163 (FITC) per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-CD163 Antibody [EDHu-1] (FITC)
Descrizione
Mouse monoclonal [EDHu-1] antibody to CD163 (FITC).
Specificità
This antibody recognises the human CD163 cell surface antigen, a 130-140 kDa glycoprotein expressed by tissue macrophages. CD163 expression may be induced on monocytes by culture in dexamethasone.Clone EDHu-1 is reported to inhibit the binding of haptoglobin/hemoglobin to CD163. Truncation mutation analysis demonstrates binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reattività
Human, Rhesus Monkey, Sheep, Pig, Guinea Pig, Bovine, Cynomolgus monkey
Immunogeno
Leucocytes harvested from the pleural cavity of patients with idiopathic spontaneous pneumothorax.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
EDHu-1
Isotipo
IgG1
Coniugare

FITC

Excitation: 490nm, Emission: 525nm

Purificazione
Protein A affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human CD163 antibody, clone EDHu-1 recognizes the human CD163 cell surface antigen, a 130-140 kDa glycoprotein expressed by tissue macrophages. CD163 expression may be induced on monocytes by culture in dexamethasone.Clone EDHu-1 is reported to inhibit the binding of haptoglobin/hemoglobin to CD163 (Madsen et al. 2004).Truncation mutation analysis demonstrates binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.
Sinonimi
C163A_HUMAN, CD 163, CD163 antigen, CD163 molecule, Hemoglobin scavenger receptor, M130, M130 antigen precursor, Macrophage associated antigen, MM130, OTTHUMP00000238617, OTTHUMP00000238618, OTTHUMP00000238619, OTTHUMP00000238620, SCARI1, Scavenger receptor cysteine rich type 1 protein M130, sCD163, Soluble CD163
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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