Anti-CD147 Antibody [BSG/7951] - BSA and Azide free
Description
Mouse monoclonal [BSG/7951] antibody to CD147.
Specificity
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Applications
ELISA, IHC-P
Positive Control
THP-1 or HSB2 cells. Human renal cell carcinoma, ovarian carcinoma or melanoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human BSG protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
BSG/7951
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
35 kDa (non-reduced) / 40 kDa (reduced)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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