Anti-CD147 Antibody [8D6] (A250069)

Anti-CD147 Antibody [8D6]

Mouse monoclonal [8D6] antibody to CD147.

This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1:100-1:20, IHC-P: 1-2 µg/ml

Human

Human T cell line Molt 13.

Mouse

Monoclonal

8D6

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

35 kDa (non-reduced) / 40 kDa (reduced)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD147 Antibody [8D6] - BSA and Azide free (A253249).

5F7, Basigin, BSG, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, HAb18G, Hepatoma-associated antigen, Leukocyte activation antigen M6