Anti-CD11c Anticorpo [CBR-p150/4G1] (A279993)

Anti-CD11c Antibody [CBR-p150/4G1] - BSA and Azide free

Mouse monoclonal [CBR-p150/4G1] antibody to CD11c.

This antibody recognises human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a ~150 kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 does not recognize CD11a, CD11b or CD18.

Flow Cytometry, IHC-Fr, Functional Assays

IHC-Fr: 5 - 10 µg/ml, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Recombinant human CD11c.

Mouse

Monoclonal

CBR-p150/4G1

IgG2a

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD11c antibody, clone CBR-p150/4G1 specifically recognizes human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a ~150 kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 does not recognize CD11a, CD11b or CD18.

95, 95 alpha chain, CD 11c, CD11 antigen like family member C, CD11 antigen-like family member C, CD11c antigen, Complement component 3 receptor 4 subunit, CR4, Integrin alpha X, Integrin alpha X chain, Integrin alpha-X, Integrin aX, Integrin subunit alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit, ITAX_HUMAN, ITGAX, Leu M5, LEU M5 alpha subunit, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150, Leukocyte adhesion receptor p150 95, Leukocyte surface antigen p150 95 alpha subunit, Leukocyte surface antigen p150 alpha subunit, Myeloid membrane antigen alpha subunit, p150, p150 95 integrin alpha chain, p150/95, SLEB6