Anti-CD11a Anticorpo [MEM-83] (A86133)

Anti-CD11a Antibody [MEM-83] - Low endotoxin, Azide free

Mouse monoclonal [MEM-83] antibody to CD11a.

This antibody reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.

Functional Studies, Flow Cytometry, IP

FUNC: This antibody directly induces the binding of T cells to purified ICAM-1. Using an in vitro-translated CDlla cDNA deletion series, the MEM-83 activation epitope was mapped to the "I" domain of the LFA-1 alpha subunit. The studies have therefore identified a novel LFA-1 activation epitope mapping to the I domain of LFA-1, which could play a role in the regulation of LFA-1 binding to ICAM-1, Flow Cytometry: 1 µg/ml.

Human

Human peripheral blood lymphocytes.

Mouse

Monoclonal

MEM-83

IgG1

Unconjugated

1 mg/ml

170-180 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

Antigen CD11A, Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, CD 11a, CD11 antigen-like family member A, CD11a antigen, Integrin Alpha L, Integrin alpha-L, Integrin gene promoter, Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide), ITAL_HUMAN, Itgal, ITGAL protein, Leukocyte adhesion glycoprotein LFA 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, Leukocyte function associated molecule 1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA 1, LFA 1 alpha, LFA 1 alpha (LFA1A), LFA 1A, LFA-1A, LFA1A, Ly15, Ly21, Lymphocyte function associated antigen 1, Lymphocyte Function Associated Antigen Type 1 alpha, Lymphocyte function associated antigen, type 1, alpha subunit, lymphocyte function-associated antigen 1, alpha polypeptide, p180