This antibody recognises human CD101, also known as Immunoglobulin superfamily member 2 (IgSF2),. Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101 or EWI-101. CD101 is a 1021 amino acid, includinng a 20 amino acid signal peptide, ~140 kDa single pass type I homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes.CD101 plays a major role in the activation of T cells by skin dendritic cells. Mouse anti Human CD101 antibody, clone BB27 has been reported to inhibit allogeneic T-cell responses.

Applicazioni

IP, Flow Cytometry, IHC-Fr

Diluizioni consigliate

Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Reattività

Human

Immunogeno

Human thymic clone B12.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

BB27

Isotipo

IgG1

Coniugare

Unconjugated

Purificazione

Protein G affinity chromatography of tissue culture supernatant.

Concentrazione

1 mg/ml

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Mouse anti Human CD101 antibody, clone BB27 recognizes human CD101, also known as Immunoglobulin superfamily member 2 (IgSF2), . Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101 or EWI-101. CD101 is a 1021 amino acid, includinng a 20 amino acid signal peptide, ~140 kDa single pass type I homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes.CD101 plays a major role in the activation of T cells by skin dendritic cells. Mouse anti Human CD101 antibody, clone BB27 has been reported to inhibit allogeneic T-cell responses (Bagot et al. 1997).

Sinonimi

CD101 molecule, cell surface glycoprotein V7, EWI-101, glu-Trp-Ile EWI motif-containing protein 101, IGSF2, Immunoglobulin superfamily member 2, Leukocyte surface protein, V7, V7 LSB

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.