Anti-CD10 Anticorpo [SN5c] (A281767)

Anti-CD10 Antibody [SN5c] - BSA and Azide free

Mouse monoclonal [SN5c] antibody to CD10.

This antibody recognises human neprilysin, also known as CD10, atriopeptidase, enkephalinase, neutral endopeptidase 24.11, skin fibroblast elastase or common acute lymphocytic leukemia antigen (CALLA). CD10 is a 749 aminoacid, ~100 kDa single pass type II transmembrane glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes.Defects in the MME gene encoding CD10 can lead to the development of the peripheral nervous system disorder, Charcot-Marie-Tooth disease 2T (CMY2T), an axonal form of Marie-Charcot-Tooth disease characterized by either dominantly inherited primary peripheral demyelinating neuropathies, designated CMT1, or primary peripheral axonal neuropathies showing axonal degeneration in the absence of any obvious myelin alteration (CMT2).

Flow Cytometry, WB, IHC-Fr, IP

Flow Cytometry: 1:100 for 0.1 mg, 1:10 for 0.2 mg - 1:200 for 0.1 mg, 1:25 for 0.2 mg, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Human

Partially purified cell membrane antigens from fresh leukemia cells.

Mouse

Monoclonal

SN5c

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD10 antibody, clone SN5c recognizes human neprilysin, also known as CD10, atriopeptidase, enkephalinase, neutral endopeptidase 24.11, skin fibroblast elastase or common acute lymphocytic leukemia antigen (CALLA). CD10 is a 749 aminoacid, ~100 kDa single pass type II transmembrane glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes.Defects in the MME gene encoding CD10 can lead to the development of the peripheral nervous system disorder, Charcot-Marie-Tooth disease 2T (CMY2T), an axonal form of Marie-Charcot-Tooth disease characterized by either dominantly inherited primary peripheral demyelinating neuropathies, designated CMT1, or primary peripheral axonal neuropathies showing axonal degeneration in the absence of any obvious myelin alteration (CMT2).

Atriopeptidase, CALLA, CD10 antigen, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24.11, Enkephalinase, EPN, Membrane metallo endopeptidase, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase), Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10), Membrane metallo endopeptidase variant 1, Membrane metallo endopeptidase variant 2, Membrane metalloendopeptidase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10, Membrane metalloendopeptidase variant 1, Membrane metalloendopeptidase variant 2, MGC126681, MGC126707, MME, NEP, Neprilysin, neprilysin-390, neprilysin-411, NEP_HUMAN, Neutral endopeptidase, Neutral endopeptidase 24.11, Neutral endopeptidase, membrane-associated, SFE, Skin fibroblast elastase