This antibody recognises calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Applicazioni

Diluizioni consigliate

WB: 1:500 - 1:2,000

Reattività

Human, Mouse, Rat

Immunogeno

Phospho-specific peptide corresponding to residues surrounding Thr286 of human CaMK II alpha.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

Lot Specific

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Conservazione

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Note generali

Rabbit anti CaMK II alpha (pThr286) antibody recognizes calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK II alpha) also known as CaM kinase II subunit alpha, when phosphorylated at threonine 286. CaMK II alpha is a member of the CAMK serine/threonine protein kinase family involved in the central nervous system, neurotransmitter release and synaptic plasticity.CaMK II alpha is activated upon binding of calcium/calmodulin, resulting in autophosphorylation at threonine 286.

Sinonimi

Alpha CaMKII, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha B subunit, Calcium/calmodulin dependent protein kinase type II alpha chain, Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase II alpha, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type IIA, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMK II alpha subunit, CaMK-II subunit alpha, Camk2a, CAMKA, CaMKII, CaMKIINalpha, EC 2.7.11.17, KCC2A_HUMAN, KIAA0968, MGC123320, MGC139375, MGC155201, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.