Anti-C Reactive Proteina Anticorpo [F03-2C7] (Biotin) (A280387)

$420

Anticorpo monoclonale [F03-2C7] di topo contro C Reactive Protein (Biotin) per ELISA.

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-C Reactive Protein Antibody [F03-2C7] (Biotin)
Descrizione
Mouse monoclonal [F03-2C7] antibody to C Reactive Protein (Biotin).
Specificità
This antibody recognises C-reactive protein (CRP). CRP is a member of the pentaxin family of proteins which target and activate various stages of the complement system. CRP is known to exist in 2 states, either as a monomer (mCRP) or as a pentamer (pCRP), where the pantamer is composed of 5 nearly identical subunits. The monomeric and pentameric forms have similar functions, but their relative abundance differs across various tissues. For example, pCRP is present in plasma, while mCRP is present mostly in the surface of damaged cells and platelets. In humans, levels of CRP increases 1,000-fold within 24 to 48 hours of infection, inflammation or tissue damage. In response to infection or tissue damage Interleukin-6, Interleukin-1 beta or glucocorticoids induce hepatocyte production of CRP. Available CRP can then detect foreign invading microorganisms, by binding carbohydrate structures. CRP is also able to bind modified low density lipoproteins and cells undergoing cell death, to assist with phagocytosis and clearance mechanisms. This is directly co-ordinated via CRP and other pentaxin proteins to prevent excessive tissue damage and clearance of any injured tissue components.This biotinylated Mouse anti Human C-reactive protein antibody, clone F03-2C7 (MCA6187B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human C-reactive protein antibody, clone F01-1G4 (MCA6186GA) as the capture antibody.
Applicazioni
ELISA
Diluizioni consigliate
ELISA: 1 µg/ml
Reattività
Human
Immunogeno
E. coli derived recombinant human full length C-Reactive Protein (Phe17-Pro224).
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
F03-2C7
Isotipo
IgG2a
Coniugare

Biotin

Purificazione
Protein G affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human C-reactive protein antibody, clone F03-2C7 recognizes, C-reactive protein (CRP). CRP is a member of the pentaxin family of proteins which target and activate various stages of the complement system. CRP is known to exist in 2 states, either as a monomer (mCRP) or as a pentamer (pCRP), where the pantamer is composed of 5 nearly identical subunits. The monomeric and pentameric forms have similar functions, but their relative abundance differs across various tissues. For example, pCRP is present in plasma, while mCRP is present mostly in the surface of damaged cells and platelets (Wu et al. 2015). In humans, levels of CRP increases 1,000-fold within 24 to 48 hours of infection, inflammation or tissue damage (Black et al. 2004). In response to infection or tissue damage Interleukin-6, Interleukin-1 beta or glucocorticoids induce hepatocyte production of CRP. Available CRP can then detect foreign invading microorganisms, by binding carbohydrate structures. CRP is also able to bind modified low density lipoproteins and cells undergoing cell death, to assist with phagocytosis and clearance mechanisms. This is directly co-ordinated via CRP and other pentaxin proteins to prevent excessive tissue damage and clearance of any injured tissue components.This biotinylated Mouse anti Human C-reactive protein antibody, clone F03-2C7 (MCA6187B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human C-reactive protein antibody, clone F01-1G4 (MCA6186GA) as the capture antibody.
Sinonimi
C reactive protein pentraxin related, C-reactive protein(1-205), CRP, CRP_HUMAN, MGC88244, Pentraxin 1, Pentraxin 1, short, PTX 1, PTX1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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