Anti-c-Myb Antibody [MYB286] (A249447)

Mouse monoclonal [MYB286] antibody to c-Myb for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-c-Myb Antibody [MYB286]
Description
Mouse monoclonal [MYB286] antibody to c-Myb.
Specificity
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Applications
ELISA
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids 119-135 of c-Myb onco protein, coupled to KLH.
Sequence
RRKVEQEGYPQESSKAG
Host
Mouse
Clonality
Monoclonal
Clone ID
MYB286
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
~75 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-c-Myb Antibody [MYB286] - BSA and Azide free (A252627).
Synonyms
MYB, Proto-oncogene c-Myb, Transcriptional activator Myb
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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