Ricombinante Anti-BRG1 Anticorpo [BRG1/8805R] (A314528)

Anti-BRG1 Antibody [BRG1/8805R]

Recombinant rabbit monoclonal [BRG1/8805R] antibody to BRG1.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/ SNF, including the NURF (nucleosome remodeling factor).

ELISA, WB, IHC-P

HeLa or HEK-293T cells. Ubiquitous nuclear expression.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 200-400) of human SMARCA4 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

BRG1/8805R

IgG

kappa

Protein A/G chromatography.

200 µg/ml

185 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ATP dependent helicase SMARCA4, ATP-dependent helicase SMARCA4, BAF 190, BAF190, BAF190A, Brahma protein like 1, BRG1 associated factor 190A, BRG1 protein, BRG1-associated factor 190A, BRM/SWI2 related gene 1, Global transcription activator homologous sequence, global transcription activator snf2l4, Homeotic gene regulator, hSNF2b, Mitotic growth and transcription activator, MRD16, Nuclear protein GRB1, Protein brahma homolog 1, Protein BRG-1, Protein BRG1, RTPS2, SMARC A4, SMARCA4, SMCA4_HUMAN, SNF2, SNF2 beta, SNF2 like 4, SNF2-beta, SNF2B, SNF2L4, SNF2LB, Sucrose nonfermenting like 4, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4, SWI2, Transcription activator BRG1