Anti-Bcl6 Anticorpo [PCRP-BCL6-1B1] (A314488)

Anti-Bcl6 Antibody [PCRP-BCL6-1B1]

Mouse monoclonal [PCRP-BCL6-1B1] antibody to Bcl6.

Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Flow Cytometry

HeLa or MCF-7 cells.

Flow Cytometry: 1-2 µg/million cells

Human

This antibody is predicted to cross react with Mouse and Rat.

Recombinant fragment (around Amino Acids 528-601) of human BCL6 protein.

Mouse

Monoclonal

PCRP-BCL6-1B1

IgG2b

Protein A/G chromatography.

200 µg/ml

95 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

B cell CLL/lymphoma 6, B cell lymphoma 6 protein, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein, BCL 5, Bcl 6, BCL-5, BCL-6, BCL5, BCL6A, BCL6_HUMAN, cys his2 zinc finger transcription factor, LAZ 3, LAZ 3 protein, LAZ3, Lymphoma associated zinc finger gene on chromosome 3, Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3), Protein LAZ-3, ZBTB 27, ZBTB27, Zinc finger and BTB domain containing protein 27, Zinc finger and BTB domain-containing protein 27, Zinc finger and BTB domain-containing protein 27 (ZBTB27), Zinc finger protein 51, Zinc Finger Protein 51 (ZNF51), zinc finger transcription factor BCL6S, ZNF 51, ZNF51