Ricombinante Anti-Bcl-6 Anticorpo [rBCL6/1475] (A249902)

Anticorpo monoclonale [rBCL6/1475] di topo contro Bcl-6 per WB.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Bcl-6 Antibody [rBCL6/1475]
Descrizione
Recombinant mouse monoclonal [rBCL6/1475] antibody to Bcl-6.
Specificità
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000 full-length human proteins. Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Applicazioni
WB
Diluizioni consigliate
WB: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 256-389, of human Bcl-6 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
rBCL6/1475
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
95 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Bcl-6 Antibody [rBCL6/1475] - BSA and Azide free (A253082).
Sinonimi
B Cell Lymphoma 6 Protein, B-cell CLL/lymphoma 6, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein transcript, BCL5, BCL6A, cys-his2 zinc finger transcription factor, LAZ3, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, ZBTB27, Zinc finger and BTB domain-containing protein 27, Zinc Finger Protein 51, zinc finger transcription factor BCL6S, ZNF51
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-Bcl-6 Anticorpo [rBCL6/1475] (A249902)

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