Ricombinante Anti-Bax Anticorpo [BAX/8960R] (A314486)

Anti-Bax Antibody [BAX/8960R]

Recombinant rabbit monoclonal [BAX/8960R] antibody to Bax.

Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

IHC-P

Jurkat, K562, HL-60, or HeLa cells. Reed-Sternberg cells in Hodgkin s lymphoma.

IHC: 1-2 µg/ml

Human

Recombinant full-length human BAX protein.

Rabbit

Monoclonal

BAX/8960R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

21 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Apoptosis regulator BAX, Bax-protein, BAXA, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, BAX_HUMAN, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4, BCL2L4, membrane isoform alpha