Ricombinante Anti-ATRX Anticorpo [ATRX/7188R] (A314481)

$765

Anticorpo monoclonale [ATRX/7188R] di coniglio contro ATRX per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-ATRX Antibody [ATRX/7188R]
Descrizione
Recombinant rabbit monoclonal [ATRX/7188R] antibody to ATRX.
Specificità
ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome
Applicazioni
IHC-P
Controllo positivo
Raji, HeLa or A431 cells. Human pancreas, adrenal, ovary, kidney, prostate or stomach.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 2200-2450) of human ATRX protein. The exact sequence is proprietary.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
ATRX/7188R
Isotipo
IgG
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
280 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
Alpha thalassemia/mental retardation syndrome X linked homolog, ATP dependent helicase ATRX, ATP-dependent helicase ATRX, ATR2, ATRX_HUMAN, DNA dependent ATPase and helicase, Helicase 2, X linked, MGC2094, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X linked helicase II, X linked nuclear protein, X-linked helicase II, X-linked nuclear protein, XH2, XNP, Znf HX, Znf-HX
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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