Anti-ATG12 Anticorpo (A283260)

$470

Anticorpo policlonale di coniglio contro ATG12 per WB e IHC-P.

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-ATG12 Antibody
Descrizione
Rabbit polyclonal antibody to ATG12.
Specificità
This antibody recognises human Autophagy-related protein 12 (ATG12).ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.There are at least two isoforms of ATG12.
Applicazioni
WB, IHC-P
Diluizioni consigliate
IHC-P: 2.5 µg/ml, WB: 0.5 - 1 µg/ml
Reattività
Human, Mouse, Rat
Immunogeno
Synthetic peptide corresponding to 16 amino acids near the N-terminus of human ATG12.
Specie ospite
Rabbit
Clonalità
Polyclonal
Isotipo
IgG
Coniugare

Unconjugated

Concentrazione
1 mg/ml
Peso molecolare
Approximately 40 kDa in human brain tissue lysate.
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Rabbit anti ATG12 (N-Terminal) antibody recognizes human Autophagy-related protein 12 (ATG12).ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.There are at least two isoforms of ATG12.
Sinonimi
Apg12, APG12-like, APG12L, ATG12 autophagy related 12 homolog, ATG12 autophagy related 12 homolog (S. cerevisiae), ATG12_HUMAN, Autophagy 12, Autophagy-related protein 12, FBR93, HAPG12, Ubiquitin-like protein ATG12
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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