Anti-ASK1 Anticorpo (A283152)

Anti-ASK1 Antibody

Rabbit polyclonal antibody to ASK1.

This antibody recognises human ASK1, also known as apoptosis signal-regulating kinase 1, MAP kinase kinase kinase or MAPKKK. ASK1 is a ~155 kDa protein belonging to the protein kinase superfamily.ASK1 is a serine/threonine kinase and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis.ASK1 is widely expressed in a variety of human tissues including the heart and pancreas.

WB, IHC-Fr

IHC-Fr: 10 µg/ml, WB: 0.5 - 1 µg/ml

Human

A peptide corresponding to amino acids near the C-terminus of human ASK1.

Rabbit

Polyclonal

IgG

Unconjugated

Approximately 155 kDa in SW1353 cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human ASK1 antibody recognises human ASK1, also known as apoptosis signal-regulating kinase 1, MAP kinase kinase kinase or MAPKKK. ASK1 is a ~155 kDa protein belonging to the protein kinase superfamily. ASK1 is a serine/threonine kinase and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis. ASK1 is widely expressed in a variety of human tissues including the heart and pancreas.

Apoptosis signal regulating kinase 1, Apoptosis signal-regulating kinase 1, ASK 1, ASK-1, M3K5, M3K5_HUMAN, MAP/ERK kinase kinase 5, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Mitogen activated protein kinase kinase kinase 5, Mitogen-activated protein kinase kinase kinase 5