Anti-ARID1A Anticorpo [ARID1A/7735] (A314480)

Anti-ARID1A Antibody [ARID1A/7735]

Mouse monoclonal [ARID1A/7735] antibody to ARID1A.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.

IHC-P

Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1900-2000) of human ARID1A protein. The exact sequence is proprietary.

Mouse

Monoclonal

ARID1A/7735

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

165-320 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

actin-dependent regulator of chromatin subfamily F member 1, ARI1A_HUMAN, ARID domain containing protein 1A, ARID domain-containing protein 1A, AT rich interactive domain 1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain containing protein 1A, AT-rich interactive domain-containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1 associated factor 250, BRG1 associated factor 250a, BRG1-associated factor 250, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, Osa homolog 1, OSA1, OSA1 nuclear protein, P270, SMARCF1, SWI like protein, SWI SNF complex protein p270, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, SWI/SNF-related