Anti-Angiotensin Converting Enzyme 1 Antibody [ACE/3762] (A248327)

Anti-Angiotensin Converting Enzyme 1 Antibody [ACE/3762]

Mouse monoclonal [ACE/3762] antibody to Angiotensin Converting Enzyme 1.

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

WB, ELISA, IHC-P

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 652-788, of human ACE protein. The exact sequence is proprietary.

Mouse

Monoclonal

ACE/3762

IgG2c

Protein A/G chromatography.

200 µg/ml

150 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Angiotensin Converting Enzyme 1 Antibody [ACE/3762] - BSA and Azide free (A251509).

Angiotensin-converting enzyme, CD143, DCP, DCP1, Dipeptidyl carboxypeptidase I, Kininase II