Anti-alpha II Spectrin Anticorpo [SPTAN1/3506] (A277811)

Anticorpo monoclonale [SPTAN1/3506] di topo contro alpha II Spectrin per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-alpha II Spectrin Antibody [SPTAN1/3506]
Descrizione
Mouse monoclonal [SPTAN1/3506] antibody to alpha II Spectrin.
Specificità
Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous α and β chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin α II, a neuronal cytoskeleton protein.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 2,351-2,475, of human alpha II Spectrin. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
SPTAN1/3506
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
240 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-alpha II Spectrin Antibody [SPTAN1/3506] - BSA and Azide free (A278399).
Sinonimi
(ALPHA)II-SPECTRIN, Alpha Fodrin, Alpha-II spectrin, brain, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, Fodrin, alpha, NEAS, Non erythrocytic spectrin alpha, non-erythroid alpha chain, SPECA, Spectrin, Spectrin alpha chain, Spectrin alpha chain brain, Spectrin alpha non erythrocytic 1, Spectrin non erythroid alpha chain, Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, nonerythroid, alpha subunit, Spna2, SPTA 2, SPTA2, SPTA2_HUMAN, SPTAN 1, SPTAN1
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-alpha II Spectrin Anticorpo [SPTAN1/3506] (A277811)

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