Anti-alpha 1 Antichymotrypsin Anticorpo [SERPINA3/4187] (A278145)

Anticorpo monoclonale [SERPINA3/4187] di topo contro alpha 1 Antichymotrypsin per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-alpha 1 Antichymotrypsin Antibody [SERPINA3/4187] - BSA and Azide free
Descrizione
Mouse monoclonal [SERPINA3/4187] antibody to alpha 1 Antichymotrypsin.
Specificità
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of α 1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants; their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 49-187, of human alpha 1 Antichymotrypsin. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
SERPINA3/4187
Isotipo
IgG2b
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
65-76 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-alpha 1 Antichymotrypsin Antibody [SERPINA3/4187] (A277557).
Sinonimi
AACT, AACT_HUMAN, ACT, Alpha-1-antichymotrypsin His-Pro-less, Antichymotrypsin, Cell growth inhibiting gene 24/25 protein, Cell growth-inhibiting gene 24/25 protein, GIG24, GIG25, Growth inhibiting protein 24, Growth inhibiting protein 25, MGC88254, Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3, Serine (or cysteine) proteinase inhibitor clade A member 3, Serine proteinase inhibitor clade A member 3, Serpin A3, Serpin family A member 3, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3, SERPINA3
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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