Ricombinante Anti-Aldose reductase Anticorpo [rAKR1B1/7295] (A314443)

$765

Anticorpo monoclonale [rAKR1B1/7295] di topo contro Aldose reductase per IF, WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Aldose reductase Antibody [rAKR1B1/7295]
Descrizione
Recombinant mouse monoclonal [rAKR1B1/7295] antibody to Aldose reductase.
Specificità
AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Applicazioni
IF, WB, IHC-P
Controllo positivo
MOLT4, Jurkat or Raji cells. Human kidney or colon carcinoma.
Diluizioni consigliate
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant human full-length AKR1B1 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
rAKR1B1/7295
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
37 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
ADR, AKR1B 1, AKR1B1, Aldehyde reductase, Aldehyde reductase 1, Aldo keto reductase family 1, member B1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), aldr 1, aldr1, ALDR_HUMAN, ALR2, AR, Lii5 2 CTCL tumor antigen, Low Km aldose reductase, MGC1804
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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