Anti-AKT1 (phospho Ser473) Anticorpo (A283546)

Anti-AKT1 (phospho Ser473) Antibody

Rabbit polyclonal antibody to AKT1 (phospho Ser473).

This antibody recognises AKT1, also known as RAC-alpha serine/threonine-protein kinase, protein kinase B alpha or Proto-oncogene c-Akt, when phosphorylated at serine 473. AKT1 is a 480 amino acid ~48 kDa protein kinase forming part of the PI3K-Akt signaling pathway, known to regulate cell growth, proliferation and survival. Phosphorylation of threonine 308 and serine 473 are required for full activation of AKT1.

WB

WB: 1:500 - 1:2,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Ser473 of human AKT1.

Rabbit

Polyclonal

IgG

Unconjugated

Liquid

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti AKT1 (pSer473) antibody recognizes AKT1, also known as RAC-alpha serine/threonine-protein kinase, protein kinase B alpha or Proto-oncogene c-Akt, when phosphorylated at serine 473. AKT1 is a 480 amino acid ~48 kDa protein kinase forming part of the PI3K-Akt signaling pathway, known to regulate cell growth, proliferation and survival. Phosphorylation of threonine 308 and serine 473 are required for full activation of AKT1.

AKT, AKT 1, AKT1_HUMAN, MGC99656, PKB, PKB-ALPHA, PRKBA, Protein kinase B, Protein Kinase B Alpha, Proto-oncogene c-Akt, RAC, RAC Alpha, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha