Ricombinante Anti-AKR1B1 Anticorpo [AKR1B1/7010R] (A277983)

Anti-AKR1B1 Antibody [AKR1B1/7010R]

Recombinant rabbit monoclonal [AKR1B1/7010R] antibody to AKR1B1.

AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.

WB, IHC-P

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human AKR1B1 protein.

Rabbit

Monoclonal

AKR1B1/7010R

IgG

Unconjugated

200 µg/ml

37 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AKR1B1 Antibody [AKR1B1/7010R] - BSA and Azide free (A278571).

ADR, AKR1B 1, Aldehyde reductase, Aldehyde reductase 1, Aldo keto reductase family 1, member B1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, aldr 1, aldr1, ALDR_HUMAN, ALR2, AR, Lii5 2 CTCL tumor antigen, Low Km aldose reductase, MGC1804