Ricombinante Anti-ACTH Anticorpo [rCLIP4278] (A278498)

Anticorpo monoclonale [rCLIP4278] di topo contro ACTH per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-ACTH Antibody [rCLIP4278] - BSA and Azide free
Descrizione
Recombinant mouse monoclonal [rCLIP4278] antibody to ACTH.
Specificità
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to CLIP (aa25-39 of ACTH); does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Synthetic peptide corresponding to amino acids 1-24 of human ACTH.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
rCLIP4278
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
ACTH is ~5 kDa / the POMC precursor is ~30 kDa.
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ACTH Antibody [rCLIP4278] (A277910).
Sinonimi
Adrenocorticotropic hormone, Adrenocorticotropin, Alpha melanocyte stimulating hormone, alpha-MSH, alphaMSH, Beta LPH, Beta melanocyte stimulating hormone, Beta-endorphin, beta-MSH, CLIP, Corticotropin, Corticotropin lipotropin, Corticotropin-like intermediary peptide, Gamma LPH, gamma-MSH, Lipotropin beta, Lipotropin gamma, Lipotropin, included, LPH, Melanocyte-stimulating hormone, included, Melanotropin alpha, Melanotropin beta, Melanotropin gamma, Melanotropin, included, Met-enkephalin, MSH, NPP, Opiomelanocortin prepropeptide, POC, POMC, Pomc-1, Pomc1, Pomc2, Pro ACTH endorphin, Pro opiomelanocortin, Pro-opiomelanocortin-alpha, Proopiomelanocortin, Proopiomelanocortin preproprotein, Tetracosactide
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-ACTH Anticorpo [rCLIP4278] (A278498)

Inizio pagina