This antibody recognises IRAK2, also known as interleukin-1 receptor associated kinase-like 2. IRAK2 is one of the putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 plays a critical role in proximal TLR signalling and in the activation of NF-kB.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human IRAK2.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 72 kDa in cell lysates and tissue lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti IRAK2 antibody recognizes IRAK2, also known as interleukin-1 receptor associated kinase-like 2. IRAK2 is one of the putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 plays a critical role in proximal TLR signalling and in the activation of NF-kB.